Parasitismo da celula muscular lisa pela «Leishmania braziliensis»
نویسندگان
چکیده
منابع مشابه
Extreme inbreeding in Leishmania braziliensis.
Leishmania species of the subgenus Viannia and especially Leishmania braziliensis are responsible for a large proportion of New World leishmaniasis cases. The reproductive mode of Leishmania species has often been assumed to be predominantly clonal, but remains unsettled. We have investigated the genetic polymorphism at 12 microsatellite loci on 124 human strains of Leishmania braziliensis from...
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New therapeutic alternatives against leishmaniasis remain a priority. The activity of azithromycin against Leishmania (Leishmania) major has been previously demonstrated. Different responses among species of Leishmania make species-specific drug screening necessary. The activity of azithromycin against Leishmania (Viannia) braziliensis and Leishmania (Leishmania) amazonensis was evaluated in go...
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This study describes the identification of aqueous-soluble antigens in Leishmania promastigotes immunologically and biochemically closely related to the major surface antigen. Proteins from surface-iodinated L. braziliensis braziliensis and L. donovani chagasì promastigotes, extracted and separated by partitioning in the detergent Triton X-114, were analyzed. Immunoblotting of the extracted pro...
متن کاملIdentification of serine proteases from Leishmania braziliensis.
Leishmania (V) braziliensis is one of the most important ethiologic agents of the two distinct forms of American tegumentary leishmaniasis (cutaneous and mucosal). The drugs of choice used in leishmaniasis therapy are significantly toxic, expensive and are associated with frequent refractory infections. Among the promising new targets for anti-protozoan chemotherapy are the proteases. In this s...
متن کاملDogs as Reservoirs for Leishmania braziliensis
based on the consideration that R. aeschlimannii is usually found in ticks of the genus Hyalomma, primarily in H. marginatum (1). Therefore, 1 of the PCRs amplifi ed a fragment of the Hyalomma tick mitochondrial cytochrome oxidase I gene and the other a fragment of the internal transcribed spacer 2 (7). The ITS2 fragment displayed the highest (99%) similarity with the respective fragment of H. ...
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ژورنال
عنوان ژورنال: Memórias do Instituto Oswaldo Cruz
سال: 1914
ISSN: 0074-0276
DOI: 10.1590/s0074-02761914000100005